Thiamine, Riboflavin, Pyridoxine, Nicotinamide and Zinc.

Indication: Treatment and prevention of B-Vitamins and Zinc deficiencies.
Dosage & Administration: Bicozin Syrup: Adults : 10 ml (2 teaspoonfuls) 2 to 3 times daily, Children : 10 ml (2 teaspoonfuls) 1 to 3 times daily, Infants : 5 ml (1 teaspoonful) 1 to 2 times daily. Bicozin Tablet: Adults & Children over 30 kg : 1 to 2 tablets 2 to 3 times daily.
Contraindication & Precaution: In patients with a known hypersinsitivity to any of the ingredients of this product.
Side Effect: Generally well tolerated.
Drug Interaction: Generally no interactions have been observed.
Use in Pregnancy and Lactation: Recommended.
Preparation: (Thiamine Hydrochloride 5 mg, Riboflavin 2 mg, Pyridoxine Hydrochloride 2 mg, Nicotinamide 20 mg and elemental Zinc 10 mg)/5 ml Syrup. (Thiamin Mononitrate 5 mg, Riboflavin 2 mg, Pyridoxine Hydrochloride 2 mg, Nicotinamide 20 mg & elemental Zinc 10 mg)/Tablet.

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Betamethasone dipropionate & Neomycin Sulphate.

Indication: Eczema, prurigo nodularis, psoriasis, neurodematoses, seborrhoeic dermatitis, contact sensitivity reactions, systemic steroid therapy in generalized erythroderma, secondarily infected insect bites and anal and genital intertrigo; specially when scondary bacterial infection is present.
Dosage & Administration: Apply sparingly 2-3 times daily. reducing frequency as condition responds.
Contraindication & Precaution: Untreated bacterial, fungal or viral skin lesions, acne and perioral dermatitits. Long-term continuous topical therapy should be avoided where possible, particularly in infants and children. If applied to the eyelids, care is needed to ensure that the preparation does not enter the eye, as glaucoma might occur.
Side Effect: Local atrophic changes in the skin such as thinning, striae, and dilatation of the superficial blood vessels, sufficient systemic absorption to produce the features of hypercorticism and suppression of the HPA axis.
Use in Pregnancy and Lactation: Topical administration of corticosteroids to pregnant animal can cause abnormalities of fetal development including cleft palate and intrauterine growth retardation and fetal ototoxicity.
Preparation: Cream (1 mg Betamethasone + 5 mg Neomycin)/gm.

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Thiamine

Indication: Beriberi and wernick’s encephaolpathy, neuritis associated with pregnancy and pellagra.
Dosage & Administration: Prophylaxis-3 to 10 mg daily. Mild chronic deficiency-10 to 25 mg daily. Severe deficiency-200 to 300 mg daily.
Contraindication & Precaution: There is no absolute contraindication.
Side Effect: Anaphylactic reaction rarely occurs. transient mild soreness might happen.
Drug Interaction: No hazardous drug interactions have been reported.
Use in Pregnancy and Lactation: The drug may be given safely to neonates, children, pregnant and lactating women and elderly patients.
Preparation: 100 mg Tablet.

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Benzathine Penicillin

Indication: Penicillin-sensitive infections, acute otitis media, syphilis, diphtheria carriers and prophylaxis against rheumatic fever and streptococcal infections.
Dosage & Administration: 0.3 to 1.2 million units up to 2.4 million units as a single dose repeated every five to seven days.
Contraindication & Precaution: History of Penicillin hypersensitivity, should not be used in infants.
Side Effect: Sensitization and allergic reactions, acute, life-threatening anaphylactic reactions are rare, but they do occur.
Drug Interaction: No potentially hazardous interactions have been described.
Use in Pregnancy and Lactation: Benzapen(R) injection should not be administered during pregnancy unless clearly indicated.
Preparation: 12 lac units/vial Injection.

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Beclomethasone

Indication: Seasonal & perennial allergic rhinitis including hay fever & non-allergic (vasomotor) rhinitis
Dosage & Administration: Adults : 02 sprays in each nostril twice daily. Children (6 to 12 years of age) : 01 spray in each nostril twice daily. Children under 6 years of age : Not recommended.
Contraindication & Precaution: History of hypersinsitivity.
Side Effect: Rare. Nasal septum perforation, sprays, dryness and irritation of the nose and throat, unpleasant taste & smell and epistaxis, wheezing, cataract reported.
Drug Interaction: None is known.
Preparation: 50 mcg/spray, Nasal spray.

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Beclomethasone

Indication: Preventive treatment for severe asthma.
Dosage & Administration: Beclomin(R) 500 ?g (2 puffs) twice daily or 250 (1 puff) four times daily.
Contraindication & Precaution: Contraindicated in patients with known sensitivity. Care is necessary in patients with active or quiescent pulmonary tuberculosis.
Side Effect: Candidiasis of the mouth and throat (thrush) occurs in some patients.
Preparation:Inhaler: 250 mcg/puff, 200 puffs.

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Beclomethasone

Indication:Preventive treatment for asthma.
Dosage & Administration: 200 ?g (2 puffs) twice daily, upto 800 ?g per day.
Contraindication & Precaution: Contraindicated in patients with known sensitivity. Care is necessary in patients with active or quiescent pulmonary tuberculosis.
Side Effect: Candidiasis of the mouth and throat (thrush) occurs in some patients.
Preparation: Inhaler: 100 mcg/puff, 200 puffs.
Beclomin(R) 250 Inhaler

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Mupirocin

Indication: Topical treatment of impetigo due to Staphylococcus aureus and Streptococcus pyogenes.
Dosage & Administration: A small amount of ointment should be applied to the affected area three times daily. The area treated may be covered with gauze dressing if desired.
Contraindication & Precaution: In individuals with a history of hypersensitivity to any of its components. If a reaction suggesting sensitivity or chemical irrritation should occur with the use of Mupirocin Ointement treatment should be discontinued and appropriate alterntive therapy for the intection should be instituted. As with other antibacterial products, prolonged use may result in overgrowth of nonsusceptible organisms, including fungi. When used on the face care should be taken to avoid the eyes.
Drug Interaction: The effect of the concurrent applicaion of Mupirocin and other drug products has not been studied.
Use in Pregnancy: The drug is classified as Pregnancy Category B. Thus, this drug should be used during pregnancy only if clearly needed.
Use in Lactation: Caution should be exercised when it is administered to a nursing woman.
Pediatric Use: The safety and effectiveness of Mupirocin have been established in the age range of 2 months to 16 years.
Adverse effects: Burning, stinging, pain, itching, rash, nausea, erythema dry skin, tenderness, swelling, contact dermatitis, and increased exudate.
Preparation: 2 % Ointment.

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Vitamin B-complex

Indication: Glossitis, stomatitis, cheilosis, beriberi polyneuritis.
Dosage & Administration: Tablet/Capsule : 1-2, 3 times daily or as directed by the physician. Syrup : 2-3 teaspoonful daily. Injection : 2 ml daily IV or IM.
Contraindication & Precaution: Hypersensitivity to the components.
Side Effect: Rarely allergic reactions.
Drug Interaction: Can decrease the effecacy of levodopa.
Use in Pregnancy and Lactation: It is safe to use B-50(R) forte in pregnancy and lactation.
Preparation: Tablet, Capsule, 100 ml & 200 ml Syrup and Injection.

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Lamivudine and Zidovrdine

Indication: Treatment of HIV infection.
Dosage & Administration: Adults and adolescents (at least 12 years of age): 1 tablet twice daily.
Contraindication & Precaution: Contraindicated in patients with previously demonstrated clinically significant hypersensitivity to any of the components of the product. Patients with Impaired Renal Function:Reduction of teh dosages of Lamivudine and Zidovudine is recommended for patients with impaired renal function. Fat Redistribution : Redistribution/accumulation of body fat including central obesity, dorso-cervical fat enlargement (buffalo hump), peripheral wasting, facial wasting, breast enlargement, and cushingoid appearance have been observed in patients receiving antiretroviral therapy. Patients with HIV and Hepititis B virus co-infection: safety & efficacy not established.
Side Effect: More common : Chills, fever, pale skin, sore throat, unusual tiredness or weakness, headache. Less common : Abdominal pain, burning, tingling, numbness, or pain in the hands, arms, feet, or legs, muscle tenderness and weakness, nausea, skin rash, vomiting, yellow eyes or skin. Coughing, decreased appetite, diarrhea, dizziness and trouble in sleeping may occur.
Drug Interaction: Lamivudine Exposure increase with : Trimethoprim/sulfamethoxazole and zalcitabine. Zidovukine Exposure increase with : Ganciclovir, interferon-alpha, and other bone marrow suppressive or cytotoxic, stavudine, ribavirin.
Use in Pregnancy and Lactation: Pregnancy Category C. This drug should be used during pregnancy only if the potential benefits outweigh the risks. Because of the potential for HIV transmission and the potential for serious adverse effects in nursing infants, mothers should be instructed not to breast-feed they are receiving this combination.
Preparation: (150 mg Lamivudine and 300 mg Zidovudine)/Tablet.

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