Albendazole

Indication: Single or mixed intestinal infection caused by various heiminths.
Dosage & Administration: For children of 12-24 months 200 mg as single dose. The usual dose for adults and children aged 2 years or over with ascariasis, enterobiasis, hookworm infestation or trichuriasis is 400 mg as single dose. In Strogyloidiasis and Taeniasis, 400 mg for three consecutive days is recommended. Adults, for alveolar hydatid disease, 400 mg twice daily for 28 days of treatment followed by 14 days without treatment may need to continue for months or years. For cystic echinococcosis the 28 days course of 400 mg twice daily may be repeated after 14 days without treatment to a total lf three treatment cycles.
Contraindication & Precaution: Albendazole should not be administered during pregnancy.
Side Effect: Epigastric pain, dry mouth, pruritus, constipation.
Use in Pregnancy and Lactation: Albendazole should not be administered during pregnancy and in women thought to be pregnant.
Preparation: 400 mg Tablet, 200 mg/5 ml Suspension.

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Cetirizine

Indication: Seasonal Allergic Rhinitis, Perennial Allergic Rhinitis, Chronic Idiopathic Urticaria, and Pruritus. It is also used in allergen induced asthma.
Dosage and Administration: Administered with or without food. Adults and Children 6 years and older:Tablet: 1 tablet daily. Syrup: 2 teaspoonfuls once daily or 1 teaspoonful twice daily. In patients with decreased renal function (Creatinine clearance 11-31 ml/min), patients on hemodialysis (Creatinine clearance less than 7 ml/min) and in hepatically impaired patients, a dose of ½ tablet or 1 teaspoonful once daily is recommended. Children 2-6 years: Syrup: 1 teaspoonful once daily or ½ teaspoonful twice daily. Children 6 months-<2 years: Syrup: ½ teaspoonful once daily. The dose in children 12-23 months of age can be increased to a maximum dose as ½ teaspoonful every 12 hours. Paediatric Drops: 1 ml, once daily. The dose in children 12-23 months of age can be increased to a maximum dose as 1 ml, every 12 hours.
Contraindications: Hypersensitivity or idiosyncrasy to cetirizine or to its parent compound, hydroxyzine.
Precaution & Warning: Caution should be exercised when driving a car or operating a heavy machinery. Concurrent use with alcohol or other CNS depressants should be avoided because additional reduction in alertness and additional impairment of CNS performance may occur.
Drug Interaction: No clinically significant drug interactions have been found.
Use in Pregnancy and Lactation: Cetirizine should be used in pregnancy only if clearly needed. Use in lactating mother is not recommended.
Preparation: 10 mg Tablet, 5 mg/5 ml Syrup, 2.5 mg/ml Paediatric Drops.

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Ketotifen

Indication: Symptomatic treatment of allergic conditions including rhinitis and conjunctivitis. Prophylactic treatment of bronchial asthma.
Dosage and Administration: Adults: 1 mg twice daily with food. If necessary the dose may be increased to 2 mg twice daily in severe cases. Children above 3 years: 1 mg twice daily with food. Patients known to be easily sedated should begin treatment with 0.5 to 1 mg at night for the first few days of as directed by the physician. Use in elderly: Same as adult dose or as advised by the physician.
Contraindication and Precaution: A reversible fall in the platelet count has been observed in a few patients receiving Ketotifen concomitantly with oral antidiabetic agent and it has beeen suggested that this combination should therefore be avoided. Although there is no evidence of any teratogenic effect, recommendations for Ketotifen in pregnancy or when breast feeding can not be given. It is important to continue the previous treatment for a minimum of two weeks after starting Ketotifen to avoid the possibility of exacerbation of asthma. This applies specially to systemic corticosteroids and ACTH because of the possible existence of adrenocortical insufficiency in steroid dependent patient. If inter current infection occurs, Ketotifen treatment must be supplemented by specific antimicrobial therapy. During the first day of treatment with Ketotifen, reactions may be impaired and patients should be warned not to take charge of vehicle or machinery until the effect of Ketotifen treatment on the individual is known. Patients should be advised to avoid alcoholic drinks. Ketotifen may potentiate the effects of sedatives, hyponotics, antihistamines and alcohol.
Side Effect: Drowsiness and in isolated cases, dry mouth and slight dizziness may occur at the beginning of treatment but usually disappera spontaneously after a few days.
Preparation: 1 mg Tablet , 1 mg/5 ml Syrup.

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Olopatadine(Eye Drops)

Indication: Indicated for the treatment of the signs and symptoms of allergic conjunctivitis.
Dosage and Administration: One drop in each affected eye two times per day at an interval of 6 to 8 hours.
Contraindication and Precaution: Olopatadine Hydrochloride ophthalmic solution is contraindicated in persons with a known hypersensitivity to Olopatadine Hydrochloride. Olopatadine Hydrochloride ophthalmic solution should not be used to treat contact lens related irritation. Patients who wear soft contact lenses should be instructed to wait at least ten minute after instilling Olopatadine Hydrochloride ophthalmic solution before they insert their contact lenses.
Use in Pregnancy and Lactation: Should be used n pregnant women only if the potential benefit to the mother justifies the potential risk to the fetus. Caution should be exercised when Olopatadine Hydrochloride ophthalmic solution is administered to a nursing mother.
Side Effect: Headaches have been reported at an incidence of 7%. The following adverse experiences have been reported in less than 5% of patients: Asthenia, blurred vision, burning or stinging. Cold syndrome, dry eye, foreign body sensation, hyperemia, hypersensitivity, keratitis, lid edema, nausea, pharyngitis, pruritus, rhinitis, sinusitis, and taste perversion.
Preparation: 0.1% Eye Drops.

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Clotrimazole

Indication:Vaginitis due Candida or Trichomonas, Super-infections with Clotrumazole-sensitive bacteria.
Dosage and Administration: 3 consecutive nights, 2 Afun(R) vaginal tablets are inserted as deeply as possible into the vagina.
Contraindication and Precaution: Hypersensitivity to Clotrimazole.
Side Effect: Local irritation or burning sensation.
Use in Pregnancy: It is recommended that Clotrimazole should be used in pregnancy only when considered necessary by the physician.
Preparation: 100 mg Vaginal Tablets with an applicator.

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